Discussion on the Effect and Clinical Availability of Rational Drug Treatment for Hypertensive Patients in Primary Hospitals

Abstract

To explore the effectiveness and clinical availability of rational drug treatment for hypertensive patients in primary hospitals. Methods: The 90 selected patients were all treated with selected medication in our hospital from August 2021 to August 2022. Following the randomized principle, the enrolled patients were divided into a control group (treated with enalapril maleate folic acid tablets, 45 cases) and an observation group (treated with nifedipine controlled release tablets, 45 cases). Analyze the clinical effect and complications after treatment and compare them between groups; The blood pressure changes before and after treatment were analyzed and compared between groups. Results: Compared with 75.56% of the clinical efficacy in the control group, 95.56% in the observation group was higher (P<0.05); Before treatment, there was no significant difference in blood pressure levels among different groups of patients (P>0.05). Compared with before treatment, diastolic and systolic blood pressure showed a significant downward trend after treatment, and the decrease was more significant in the observation group (P<0.05); The incidence of adverse reactions in the control group was 6.66%, while the incidence of complications in the observation group was 11.11% (P>0.05). Conclusion: Rational drug treatment for hypertensive patients in primary hospitals has a good effect, can stabilize their blood pressure within the normal range, and combined medication will not increase adverse drug reactions. The safety is worth affirming.